Saliva sampling offers an easy and non-invasive method as compared with plasma sampling. |
Azithromycin pharmacokinetics and bioequivalence metrics in saliva were compared with plasma, and a good correlation was demonstrated. |
Azithromycin is considered a class I drug based on the Salivary Excretion Classification System (SECS), and saliva sampling could be used as an alternative to plasma sampling to characterize the drug’s pharmacokinetics and bioequivalence in humans. |