Table 1.
Baseline patient characteristics in the unmatched and propensity score-matched groups
| Variable | Unmatched groups | Matched groups | ||||
|---|---|---|---|---|---|---|
| Control (n = 3071) | Antithrombin (n = 152) | Standardized differences (%) | Control (n = 103) | Antithrombin (n = 103) | Standardized differences (%) | |
| Age, years (SD) | 56.2 (26.5) | 62.7 (22.0) | −27.0 | 63.6 (21.3) | 61.6 (21.8) | 9.2 |
| Sex (male) | 1887 (61.4) | 97 (63.8) | −4.9 | 66 (64.1) | 68 (66.0) | −4.1 |
| Burn index, mean (SD) | 21.7 (17.1) | 40.5 (23.4) | −91.8 | 38.5 (23.9) | 37.1 (22.1) | 6.0 |
| Inhalation injury without mechanical ventilation | 188 (6.1) | 1 (0.7) | 30.5 | 1 (1.0) | 1 (1.0) | 0.0 |
| Mechanical ventilation | 651 (21.2) | 124 (81.6) | −151.6 | 83 (80.6) | 79 (76.7) | 9.5 |
| Charlson Comorbidity Index ≥ 1 | 409 (13.3) | 11 (7.2) | 20.1 | 8 (7.8) | 7 (6.8) | 3.7 |
| Academic hospital | 1097 (35.7) | 108 (71.1) | −75.7 | 67 (65.0) | 69 (67.0) | −4.1 |
| Hospital volume, cases | ||||||
| Low | 1163 (37.9) | 14 (9.2) | 71.8 | 13 (12.6) | 12 (11.7) | 3.0 |
| Medium | 942 (30.7) | 59 (38.8) | −17.2 | 44 (42.7) | 38 (36.9) | 11.9 |
| High | 966 (31.5) | 79 (52.0) | −42.5 | 46 (44.7) | 53 (51.5) | −13.6 |
| Consciousness level | 0.0 | |||||
| Alert | 2230 (72.6) | 62 (40.8) | 67.8 | 40 (38.8) | 45 (43.7) | −9.9 |
| Delirium | 459 (14.9) | 38 (25.0) | −25.3 | 34 (33.0) | 27 (26.2) | 14.9 |
| Somnolence | 129 (4.2) | 15 (9.9) | −22.3 | 9 (8.7) | 11 (10.7) | −6.6 |
| Coma | 253 (8.2) | 37 (24.3) | −44.7 | 20 (19.4) | 20 (19.4) | 0.0 |
| Antibiotics use | 1229 (40.0) | 114 (75.0) | −75.7 | 76 (73.8) | 74 (71.8) | 4.4 |
| Catecholamines | ||||||
| Dopamine use | 233 (7.6) | 44 (28.9) | −57.5 | 31 (30.1) | 27 (26.2) | 8.6 |
| Dobutamine use | 47 (1.5) | 13 (8.6) | −32.5 | 6 (5.8) | 9 (8.7) | −11.2 |
| Noradrenaline use | 139 (4.5) | 28 (18.4) | −44.7 | 15 (14.6) | 14 (13.6) | 2.8 |
| Escharotomy performed | 130 (4.2) | 23 (15.1) | −37.5 | 16 (15.5) | 18 (17.5) | −5.2 |
| Debridement performed | 127 (4.1) | 10 (6.6) | −10.9 | 7 (6.8) | 6 (5.8) | 4.0 |
| Red blood cell use | 109 (3.5) | 39 (25.7) | −65.9 | 23 (22.3) | 21 (20.4) | 4.7 |
| Fresh-frozen plasma use | 217 (7.1) | 81 (53.3) | −116.5 | 44 (42.7) | 45 (43.7) | −2.0 |
| Platelet use | 19 (0.6) | 15 (9.9) | −42.4 | 5 (4.9) | 4 (3.9) | 4.8 |
| Albumin use | 608 (19.8) | 133 (87.5) | −184.9 | 89 (86.4) | 87 (84.5) | 5.5 |
| Haptoglobin use | 196 (6.4) | 67 (44.1) | −96.3 | 31 (30.1) | 31 (30.1) | 0.0 |
| Heparin use | 644 (21.0) | 110 (72.4) | −120.2 | 73 (70.9) | 72 (69.9) | 2.1 |
| Thrombomodulin use | 14 (0.5) | 30 (19.7) | −67.5 | 4 (3.9) | 5 (4.9) | −4.8 |
| Gabexate mesilate use | 25 (0.8) | 15 (9.9) | −41.1 | 5 (4.9) | 6 (5.8) | −4.3 |
| Nafamostat mesilate use | 57 (1.9) | 19 (12.5) | −42.1 | 16 (15.5) | 16 (15.5) | 0.0 |
| Ulinastatin use | 50 (1.6) | 20 (13.2) | −45.2 | 9 (8.7) | 11 (10.7) | −6.6 |
SD standard deviation