Table 1.
Descriptive statistics
| All patients n = 54 | Non‐ON n = 32 | |
|---|---|---|
| Gender | ||
| Male (%) | 22 (41) | 12 (38) |
| Female (%) | 32 (59) | 20 (63) |
| Age (years) | ||
| Mean (SD) | 40.5 (10) | 39.9 (9.9) |
| Disease duration (years) | ||
| Mean (SD) | 7.6 (6.7) | 7.9 (5.7) |
| EDSS | ||
| Median (range) | 2 (0–4) | 2 (0–4) |
| History of ON | ||
| n (%) | 18 (36%) | n.a. |
| Currently treated | ||
| n (%) | 32 (59%) | 24 (75%) |
| pRNFL (μm) | ||
| Mean (SD) | 84.2 (11.2) | 86.9 (12.1) |
| mRNFL (mm³) | ||
| Mean (SD) | 0.16 (0.02) | 0.17 (0.19) |
| mGCLIPL (mm³) | ||
| Mean (SD) | 0.55 (0.07) | 0.56 (0.08) |
| TMV (mm³) | ||
| Mean (sd) | 2.32 (0.12) | 2.33 (0.14) |
| BV (cm³) | ||
| Mean (SD) | 1219.8 (114.9) | 1209.5 (90.2) |
| GMV (cm³) | ||
| Mean (SD) | 636.9 (56.9) | 623.4 (41.3) |
| WMV (cm³) | ||
| Mean (SD) | 582.9 (62.6) | 586.1 (55.4) |
EDSS, Expanded Disability Status Scale; ON, optic neuritis; pRNFL, peripapillary retinal nerve fiber layer; mRNFL, macular retinal nerve fiber layer; TMV, total macular volume; mGCLIPL, macular ganglion cell/inner plexiform layer; BV, brain volume; GMV, gray matter volume; WMV, white matter volume; SD, standard deviation.
TMV, mRNFL, and mGCLIPL values for 3 mm diameter cylinder centered at the fovea centralis.