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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Cell Rep. 2016 Sep 20;16(12):3260–3272. doi: 10.1016/j.celrep.2016.07.052

Figure 6. iNKT cell behaviour after S. pneumoniae infections emulates that observed after α-Galcer treatment. CCL17 signaling is crucial for survival against S. pneumoniae infections.

Figure 6

A. Quantification of CXCR6GFP+ iNKT cell behavior after aerosolized S.pneumoniae using IVM. B. Quantification of CXCR6GFP+ iNKT cell localization based on IVM and TRITC-dextran shadowing in mice infected with S.pneumoniae. C. Quantification of iNKT cell localization after S.pneumoniae based on CD45 IV staining and flow cytometry. D. Survival analysis of mice treated with CCL17 neutralizing antibody. Survival was a significantly different between CCL17 treated mice and control mice based on Mantel-Cox test (p = 0.006). Error bars represent standard error of mean. N = 3–5 animals per group.