Table 3.
Values of the width of keratinized tissue (mm) at baseline and final evaluation, postintervention gain (mm), mean difference in gain (mm) between test and control groups, graft contraction (%), and frequency of postintervention KT width ≥2 mm (%)
| Study (year) | Group | Baseline (mm) | Final evaluation | Graft contraction (%) | Frequency of postintervention KT width ≥2 mm (range or 95% CI of postintervention KT width) | |||
|---|---|---|---|---|---|---|---|---|
| Values (mm) | Gain (mm) | Mean difference in gain (mm) | Comparison based on | |||||
| Acellular matrices | ||||||||
| Wei et al. (2000) [17] | Test | 0.68 ± 0.26a | 3.25 ± 0.89 a | 2.59 ± 0.92 a | 2.98c | A, B, C | 71 ± 10 a | NR |
| Control | 0.57 ± 0.41a | 6.15 ± 0.49 a | 5.57 ± 0.44 a | 16 ± 12 a | NR | |||
| Harris (2001) [10] | Test | 0.6 ± 0.87a | 4.7 ± 1.92 a | 4.1 ± 1.79a | A, C | NR | <100% (range 1.5–8.5 mm) | |
| Control (FGG) | 0.8 ± 0.59a | 4.8 ± 1.16 a | 4.1 ± 1.25a | 0.00c | 100% (range 3.0–6.5 mm) | |||
| Control (CTG) | 0.4 ± 0.47a | 4.0 ± 0.99 a | 3.6 ± 0.82a | 0.50c | 100% (range 2.5–5.5 mm) | |||
| Nevins et al. (2010) [15] | Test | 0.8 ± 0.7a | 3.4 ± 0.8 a | 2.6 ± 1.1 a | 2.7c | A, C | NR | 100% (range 2.5–5.0 mm) |
| Control | 1.1 ± 1.1a | 6.4 ± 0.9 a | 5.3 ± 1.3 a | 100% (range 5.0–8.0 mm) | ||||
| Nevins et al. (2011) [16] | Test | NR | NR | 2.3 ± 1.1a | 0.80c | A, C | NR | NR |
| Control | NR | NR | 3.1 ± 0.6a | NR | ||||
| McGuire & Scheyer (2014) [14] | Test | 0.88 ± 0.61a | 2.92 ± 0.88 a | 2.04 c | 1.61c | B, C | NR | 96.67% (95% CI 2.59–3.25 mm) |
| Control | 0.77 ± 0.68a | 4.42 ± 0.64 a | 3.65 c | NR (95% CI 4.18–4.66 mm) | ||||
| Tissue engineered | ||||||||
| McGuire & Nunn (2005) [11] | Test | 1.46 ± 0.91a | 2.72 (2.42–3.03)b | 1.26c | 1.31c | B | 45.5 (39.5–51.4)b | NR (95% CI 2.42–3.03 mm) |
| Control | 1.34 ± 0.97a | 3.91 (3.61–4.22)b | 2.57c | 21.8 (15.9–27.7)b | NR (95% CI 3.61–4.22 mm) | |||
| McGuire et al. (2008) [12] | Test | 1.07 (0.89–1.25)b | 2.40 (2.08–2.72)b | 1.33 (0.95–1.71)b | 1.96c | A, B, C | NR | 76% (95% CI 2.08–2.72 mm) |
| Control | 1.17 (0.99–1.35)b | 4.46 (4.14–4.78)b | 3.29 (2.91–3.68)b | 100% (95% CI 4.14–4.78 mm) | ||||
| McGuire et al. (2011) [13] | Test | 1.41 ± 0.72a | 3.21 ± 1.14 a | 1.80c | 1.34c | B | NR | 95.3% (NR) |
| Control | 1.43 ± 0.69a | 4.57 ± 1.00 a | 3.14c | NR | ||||
Italic values indicate significant difference (p < 0.05)
CTG connective tissue graft, FGG free gingival graft, KT keratinized tissue, NR not reported, SD standard deviation, A comparisons between baseline and final evaluation values, B comparisons between groups regarded values of KT width at the final evaluation, C comparisons between groups regarded values of KT width gain
aMean (±SD)
bMean (95% CI)
cMean (calculation based on the presented data)