Fig. 5. Changes of specific anti-house dust mite immunoglobulin E serum levels during sublingual immunotherapy. ^*The differences of reduction in eczema area and severity index (EASI) score between monosensitized and polysensitized group was analyzed statistically by using Mann-Whitney test. Mono-sensitized patients: sensitized to only Dermatophagoides pteronyssinus and D. farinae. Poly-sensitized patients: simultaneously sensitized to house dust mite and other allergens proven by multiple allergen simultaneous test (Grade ≥3).