Fig. 3. The increased expression of insulin-like growth factor (IGF)1R and IGFBP2 in cultured sebocytes after treatment with IGF-1. In addition, the increased gene expression of sterol response element-binding protein (SREBP) and phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PI3KCA) after treatment of cultured sebocytes with IGF-1.
