Fig. 4. Effects of 1% eupatilin on mRNA expression of thymic stromal lymphopoietin (TSLP), tumor necrosis factor (TNF)-α, interleukin (IL)-4, IL-5, IL-13, IL-19, and interferon (IFN-γ) in the ears of NC/Nga mice. 1% eupatilin cream also significantly decreased the mRNA expression of TSLP, TNF-α, IL-4, and IL-19, but not of IL-5, IL-13, and IFN-γ, compared to the vehicle (p<0.05). Non-treated (NT), 2,4-dinitrochlorobenzene (DNCB)+vehicle (VH), DNCB+1% eupatilin cream, DNCB+0.03% tacrolimus ointment. Data are presented as mean±standard error of the mean (n=5). ^*p<0.05, compared to the vehicle (VH) group. RFI: relapse-free interval.