Table 1.
ABIDE substudies and corresponding objectives and patient cohorts
| Substudy | Objective | Cohort | Data collection | Sample |
Measures |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of patients | Setting | Population | MRI | CSF | PET | CON | ||||
| 1 | 1A, B | Prospective | Cross-sectional | n = 200 | Local | Mixed | √ | √ | ||
| 2 | 1C | Prospective | Longitudinal | n = 450 | Tertiary | Mixed | √ | √ | √ | |
| 2 | 1C | Prospective | Longitudinal | n = 50 | Tertiary | MCI | √ | √ | √ | |
| 3 | 2A, B | Retrospective | Longitudinal | n = 400 | Tertiary | MCI | √ | √ | ||
| 4 | 3 | Prospective | Cross-sectional | n = 120 | Local | Mixed | (√) | (√) | √ | |
Abbreviations: ABIDE, Alzheimer's biomarkers in daily practice; MRI, magnetic resonance imaging; CSF, cerebrospinal fluid; PET, positron emission tomography; CON, memory clinic consultation between clinician and patient and caregiver(s); MCI, mild cognitive impairment.