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. 2017 Feb 20;4(1):ENEURO.0128-16.2017. doi: 10.1523/ENEURO.0128-16.2017

Table 2:

Pharmacokinetic data of rhCDNF in the striatum after intrastriatal infusion

High dose Low dose Ratio
Cmax (ng/mg) 140.6 20.6 6.8
AUC0-t (µg/mg x min) 1.143 0.208 5.5
Half-life (h) 5.51 5.55