Table 1.
Incidence and characteristics of patients discharged with a diagnosis of idiopathic pulmonary fibrosis
| Year | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gender, n (%)* | |||||||||||
| Male | 909 (55.49) | 919 (54.7) | 990 (56.9) | 1039 (55.06) | 1043 (55.48) | 1231 (57.58) | 1378 (56.43) | 1501 (56.43) | 1756 (60.59) | 1973 (60.69) | 12 739 (57.35) |
| Female | 729 (44.51) | 761 (45.3) | 750 (43.1) | 848 (44.94) | 837 (44.52) | 907 (42.42) | 1064 (43.57) | 1159 (43.57) | 1142 (39.41) | 1278 (39.31) | 9475 (42.65) |
| Age, years* | |||||||||||
| Mean (SD) | 72.16 (11.56) | 71.34 (12.85) | 70.74 (13.25) | 72.67 (12.24) | 72.49 (12.46) | 73.15 (12.44) | 73.52 (12.2) | 73.87 (12.25) | 74.04 (11.71) | 74.62 (11.81) | 73.11 (12.28) |
| Age groups, n (%)* | |||||||||||
| 0–49 years | 80 (4.88) | 102 (6.07) | 117 (6.72) | 99 (5.25) | 98 (5.21) | 102 (4.77) | 103 (4.22) | 105 (3.95) | 108 (3.73) | 119 (3.66) | 1033 (4.65) |
| 50–64 years | 220 (13.43) | 301 (17.92) | 295 (16.95) | 287 (15.21) | 285 (15.16) | 315 (14.73) | 352 (14.41) | 391 (14.7) | 466 (16.08) | 451 (13.87) | 3363 (15.14) |
| 65–79 years | 916 (55.92) | 804 (47.86) | 908 (52.18) | 928 (49.18) | 931 (49.52) | 1007 (47.1) | 1182 (48.4) | 1235 (46.43) | 1254 (43.27) | 1435(44.14) | 10 600 (47.72) |
| ≥80 years | 422 (25.76) | 473 (28.15) | 420 (24.14) | 573 (30.37) | 566 (30.11) | 714 (33.4) | 805 (32.96) | 929 (34.92) | 1070 (36.92) | 1246 (38.33) | 7218 (32.49) |
| Charlson index, n (%)* | |||||||||||
| 0 | 807 (49.27) | 872 (51.9) | 861 (49.48) | 883 (46.79) | 824 (43.83) | 912 (42.66) | 977 (40.01) | 1079 (40.56) | 1103 (38.06) | 1157 (35.59) | 9475 (42.65) |
| 1 | 583 (35.59) | 565 (33.63) | 619 (35.57) | 641 (33.97) | 678 (36.06) | 759 (35.5) | 899 (36.81) | 991 (37.26) | 1060 (36.58) | 1218 (37.47) | 8013 (36.07) |
| ≥2 | 248 (15.14) | 243 (14.46) | 260 (14.94) | 363 (19.24) | 378 (20.11) | 467 (21.84) | 566 (23.18) | 590 (22.18) | 735 (25.36) | 876 (26.95) | 4726 (21.27) |
| Lung transplant* | |||||||||||
| No | 1624 (99.15) | 1659 (98.75) | 1716 (98.62) | 1874 (99.31) | 1861 (98.99) | 2119 (99.11) | 2433 (99.63) | 2639 (99.21) | 2870 (99.03) | 3212 (98.8) | 22 007 (99.07) |
| Yes | 14 (0.85) | 21 (1.25) | 24 (1.38) | 13 (0.69) | 19 (1.01) | 19 (0.89) | 9 (0.37) | 21 (0.79) | 28 (0.97) | 39 (1.2) | 207 (0.93) |
| Invasive mechanical ventilation, n (%) | |||||||||||
| No | 1600 (97.68) | 1625 (96.73) | 1689 (97.07) | 1846 (97.83) | 1832 (97.45) | 2086 (97.57) | 2403 (98.4) | 2592 (97.44) | 2830 (97.65) | 3179 (97.79) | 21 682 (97.61) |
| Yes | 38 (2.32) | 55 (3.27) | 51 (2.93) | 41 (2.17) | 48 (2.55) | 52 (2.43) | 39 (1.6) | 68 (2.56) | 68 (2.35) | 72 (2.21) | 532 (2.39) |
| Non-invasive mechanical ventilation, n (%)* | |||||||||||
| No | 1613 (98.47) | 1647 (98.04) | 1711 (98.33) | 1838 (97.4) | 1838 (97.77) | 2080 (97.29) | 2349 (96.19) | 2566 (96.47) | 2772 (95.65) | 3096 (95.23) | 21 510 (96.83) |
| Yes | 25 (1.53) | 33 (1.96) | 29 (1.67) | 49 (2.6) | 42 (2.23) | 58 (2.71) | 93 (3.81) | 94 (3.53) | 126 (4.35) | 155 (4.77) | 704 (3.17) |
| Thoracic CT, n (%) | |||||||||||
| No | 1229 (75.03) | 1263 (75.18) | 1335 (76.72) | 1441 (76.36) | 1398 (74.36) | 1609 (75.26) | 1851 (75.8) | 1993 (74.92) | 2170 (74.88) | 2424 (74.56) | 16 713 (75.24) |
| Yes | 409 (24.97) | 417 (24.82) | 405 (23.28) | 446 (23.64) | 482 (25.64) | 529 (24.74) | 591 (24.2) | 667 (25.08) | 728 (25.12) | 827 (25.44) | 5501 (24.76) |
| Pulmonary biopsy, n(%)* | |||||||||||
| No | 1463 (89.32) | 1501 (89.35) | 1533 (88.1) | 1708 (90.51) | 1704 (90.64) | 1935 (90.51) | 2237 (91.61) | 2429 (91.32) | 2654 (91.58) | 2957 (90.96) | 20 121 (90.58) |
| Yes | 175 (10.68) | 179 (10.65) | 207 (11.9) | 179 (9.49) | 176 (9.36) | 203 (9.49) | 205 (8.39) | 231 (8.68) | 244 (8.42) | 294 (9.04) | 2093 (9.42) |
| In-hospital mortality, n (%) | |||||||||||
| No | 1396 (85.23) | 1415 (84.23) | 1515 (87.07) | 1612 (85.43) | 1602 (85.21) | 1849 (86.48) | 2117 (86.69) | 2268 (85.26) | 2485 (85.75) | 2805 (86.28) | 19 064 (85.82) |
| Yes | 242 (14.77) | 265 (15.77) | 225 (12.93) | 275 (14.57) | 278 (14.79) | 289 (13.52) | 325 (13.31) | 392 (14.74) | 413 (14.25) | 446 (13.72) | 3150 (14.18) |
| Length of stay, days* | |||||||||||
| Mean (SD) | 11.87 (11.18) | 12.11 (11.77) | 11.64 (11.7) | 11.15 (10.56) | 11.33 (12.54) | 10.81 (11.81) | 10.4 (9.59) | 10.5 (10.64) | 10.38 (12.31) | 10.2 (11.12) | 10.9 (11.34) |
| Cost in €* | |||||||||||
| Mean (SD) | 4838.51 (5692.3) | 5199.7 (7525.26) | 5055.8 (6285.74) | 4631.99 (4175.69) | 5330.68 (5949.12) | 5551.34 (6490.03) | 4901.52 (6854.64) | 5684.58 (10074.78) | 5465.39 (9238.99) | 5410.9 (9439.5) | 5249.35 (7737.83) |
| Total* | |||||||||||
| N | 1638 | 1680 | 1740 | 1887 | 1880 | 2138 | 2442 | 2660 | 2898 | 3251 | 22 214 |
| Incidence+ | 3.82 | 3.85 | 3.92 | 4.17 | 4.09 | 4.61 | 5.24 | 5.69 | 6.2 | 6.98 | 4.88 |
*p<0.05 for time trend.