Figure 4. Effect of PLE on pro-angiogenic factor secretion of HCT116 human colon cancer cells and H1299 human lung cancer cells. HCT116 (A) and H1299 (B) cells were incubated with different concentrations of MLE (0-700 µg/ml) for 24 h. The culture media was then collected, and levels of VEGF and bFGF were determined by ELISA. Statistically significant differences among groups were indicated with different letters (a-c, p<0.05 by Duncan test).
