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. 2017 Feb 21;7:42926. doi: 10.1038/srep42926

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Representative composite images of cropped GluA4, NR1, NR2A, and NR2B immunoblots with markers Pan-Cadherin and PSD-95. (b) Scatter-column combination charts depicting the expression of GluA4 and GluA2, as well as NR1, NR2A, and NR2B subunits in the synaptic membrane fraction of E (epileptic, n = 4 from 4 litters) stargazer thalamus relative to NE (non-epileptic, n = 6 from 4 litters) controls after normalization to Pan-Cadherin (*p ≤ 0.05, ** ≤ 0.01). (c) Scatter-column combination charts depicting the expression of GluA4 and GluA2 subunits in the extrasynaptic membrane fraction of E (epileptic, n = 4 from 4 litters) stargazer thalamus relative to NE (non-epileptic, n = 6 from 4 litters) controls after normalization to Pan-Cadherin (p > 0.05). Scatter-column combination charts depicting extrasynaptic to synaptic GluA subunit ratios in NE controls and E stargazers (** ≤ 0.01, *p ≤ 0.05).