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. 2016 Dec 14;2(4):213–218. doi: 10.1159/000452998

Table 1.

Characteristics of included samples in this meta-analysis

Data source
Ruderfer et al. [5], 2014 Saito et al. [11], 2014 Grigoroiu-Serbanescu et al. [13], 2015 PGC Cross-Disorder Group [4], 2013 CONVERGE Consortium [12], 2015
Phenotype BPD BPD BPD MDD MDD
Diagnostic criteria DSM-IV, DSM-IIR, RDC DSM-IV DSM-IV DSM-IV DSM-IV
Cases, n 10,410 1,012 461 9,227 5,303
Controls, n 10,700 993 436 7,383 5,337
Genotyping method Multiple Sequenom iPLEX Illumina Multiple Illumina Hi-Seq

rs7914558
p value 0.0198 0.387 0.300 0.00245 0.255
OR 1.051 1.060 1.100 1.074 1.036
95% CI 1.008–1.096 0.931–1.206 0.918–1.317 1.026–1.125 0.981–1.095

rs7085104
p value 0.00571 N/A N/A 0.00198 0.0861
OR 1.063 N/A N/A 1.078 1.054
95% CI 1.018–1.110 N/A N/A 1.028–1.130 0.998–1.113

rs11191580
p value 0.0120 0.391 0.240 0.0220 0.0231
OR 1.098 1.064 1.244 1.098 1.075
95% CI 1.021–1.181 0.918–1.232 0.913–1.695 1.013–1.190 1.012–1.143

BPD, bipolar disorder; MDD, major depressive disorder; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, fourth edition; DSM-IIR, Diagnostic and Statistical Manual of Mental Disorders, second edition, revised; RDC, Research Diagnostic Criteria; OR, odds ratio; CI, confidence interval; N/A, not available.