. 2017 Feb 21;7:43011. doi: 10.1038/srep43011

Table 5. Association of environmental exposures and DUSP1 methylation in tumour DNA by ER and PR status.

Environmental factors (%)	ER−			ER+			PR−			PR+
Environmental factors (%)	Meth^a	Unmeth^b	OR_adj^c (95%CI) P-value	Meth^a	Unmeth^b	OR_adj^c (95%CI) P-value	Meth^a	Unmeth^b	OR_adj^c (95%CI) P-value	Meth^a	Unmeth^b	OR_adj^c (95%CI) P-value
Soybean (times/week)
≤1	29	19	1.000	43	47	1.000	36	27	1.000	36	39	1.000
>1	50	11	2.978 (1.245–7.124) 0.017	68	48	1.548 (0.889–2.696) 0.159	62	17	2.735 (1.315–5.692) 0.010	56	42	1.444 (0.789–2.643) 0.282
Menstrual regularity
Yes	58	21	1.000	75	84	1.000	69	31	1.000	64	74	1.000
No	19	10	0.688 (0.276–1.716) 0.475	35	11	3.564 (1.691–7.511) 0.001	27	13	0.933 (0.425–2.047) 0.863	27	8	3.902 (1.656–9.194) 0.001

^aMeth, methylated; ^bUnmeth, unmethylated; ^cOR_adj, odds ratio generated by multivariate logistic regression; 95%CI, 95% confidence interval.