Table 2. GNAQ/GNA11 mutation status and time on study treatment in the 23 uveal melanoma patients.
Patient # | GNAQ mutation | GNA11 mutation | Months on study treatmenta |
---|---|---|---|
1 | UNK | UNK | 24.5+ |
2 | UNK | UNK | 19.9+ |
3 | UNK | UNK | 14.9+ |
4 | UNK | UNK | 14.6+ |
5 | UNK | UNK | 11.6 |
6 | R183Q | ND | 10.3 |
7 | UNK | UNK | 9.7 |
8 | ND | Q209L | 8.7 |
9 | UNK | UNK | 6.5 |
10 | UNK | UNK | 5.0 |
11 | UNK | UNK | 4.6 |
12 | ND | UNK | 4.3 |
13 | UNK | UNK | 3.5 |
14 | ND | R183C | 3.0 |
15 | Q209P | UNK | 3.0 |
16 | Q209P | ND | 2.3 |
17 | ND | Q209L | 2.1 |
18 | Q209P | UNK | 1.8 |
19 | UNK | UNK | 1.7 |
20 | ND | Q209L | 1.4 |
21 | Q209L | ND | 1.4 |
22 | UNK | UNK | 1.4 |
23 | UNK | UNK | 1.3 |
Abbreviations: ND=not detected; UNK=unknown.
Months with a plus (+) indicate patients who remain on study treatment as of the data cutoff.