Fig. 11.

Manananggal’s visual representation of alternative splicing events in CD44. The coverage plot at the top shows that multiple exons are only expressed in the PC3E samples. These alternatively spliced exons are also highlighted on the meta exon track. One exon appears to have a higher expression in GS689_Li samples. However, this exon overlaps an exon of an antisense transcript (indicated by the red box on the AS transcripts track) and thus does not represent a valid alternative splicing event. The isoforms shown at the bottom were selected in a way that represents the coverage plot best. Please note that some of these isoforms (especially the last two) might represent incomplete transcripts that are included in the gene reference