Table 1.

Association of rs612529 with AD

Referencesa	Populationb	Casesc (n)	Controlsd (n)	Effect allelee	Effect allele frequencyf	OR (95% CI)g	P valueh
[15]	Caucasian	1200	2270	C	0.209	1.12 (1.15–1.29)	1.26 × 10–3
[14]	Chinese	1012	1362	C	0.322	1.15 (1.07–1.30)	2.6 × 10–2
[12, 13]	Chinese	324	486	C	0.36	1.29 (1.10–1.45)	4 × 10–6
	Combined	2536	4118				1.14 × 10 –6

^aInitial study describing the cohorts used for association

^bEthnicity of the population under study

^cNumber of atopic dermatitis cases

^dNumber of controls

^eAllele used for the calculating the odds ratio statistics

^fAllele frequency of the effect allele in the individual study population

^gOdds ratio estimated with 95% confidence interval

^h P value estimated for the case control association study for atopic dermatitis phenotype in the individual study population

Meta P value is the P value calculated for all three cohorts combined using the Stoufier’s z trend meta-analysis which considers individual study P value sample sizes and effect directions using Meta P program [20]