Table 2.

Plasma D-dimer, fibrinogen, and CA19-9 at various stages of PC

Serum test	Relapse-free stage	Progressive disease	z/t	p
D-dimer (ng/ml)	485.18 (289.84)	1059.2 (1690.1)	−7.490	<0.001
Fibrinogen (g/l)	2.75 ± 0.52	3.71 ± 0.83	−10.228	<0.001
CA19-9 (U/ml)	24.5 (30)	207.2 (681.8)	−8.669	<0.001

Eight patients were excluded because they also had deep vein thrombosis, and two were excluded for serious infections. Samples from patients considered at relapse-free stage were extracted 1.8 months (median) before progressive. Samples from patients considered progressive disease were extracted 5 days (median) before progressive disease