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. 2017 Feb 20;15:6. doi: 10.1186/s12959-017-0129-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Reversal of the rivaroxaban effect by reversal agents shown in representative thrombograms. Thrombin generation was obtained by Calibrated Automated Thrombogram (CAT) on platelet-poor plasma. Thrombograms of the controls and patient samples of rivaroxaban-treated patients with and without reversal agents added. The reversal agents shown are prothrombin complex concentrate (PCC), activated PCC (aPCC) and recombinant factor VIIa (rFVIIa) in 100% dose