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. 2017 Feb 21;18:14. doi: 10.1186/s40360-017-0118-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Inhibition of the EGFR-Ras-Raf signaling pathway on NCI-H460 cells with combination treatment. The protein expression level of p-EGFR, total Ras, p-Raf, and p-ERK1/2 was inhibited in cells with gefitinib and Kv blockers (TEA and 4-AP) or an opener (flupirtine)