Fig. 4.

Exhaustion and senescence following T cell selection. a PD1 expression of CD8⁺ and CD4⁺ T cells following selection prior to, or post 14 days expansion ex vivo. Statistical analysis was performed using two separate one-way ANOVAS. b CD8⁺ and c CD4⁺ T cell subpopulations of memory precursor effector cells (MPECs) KLRG1⁻ CD127⁺, double positive effector cells (DPECs) KLRG1⁺ CD127⁺, short lived effector cells (SLECs) KLRG1⁺ CD127⁻ or early effector cells (EECs) KLRG1⁻CD127⁻ following selection prior to, or post 14 days expansion ex vivo. Error bars show ± SEM