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Experimental peritonitis with sepsis. (A) Peritonitis and sepsis were produced in mice by cecal ligation and puncture. Mice fed a high-fat diet (upper curve) displayed enhanced survival (34). In (B), the data from (A) are presented again as Study 1. Survival after cecal ligation and puncture of C57BL/6 mice that were fed a high-fat diet for 12 wks were compared with those on a regular diet. Survival of controls without the operation was 100% (35).
