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Identification of mutations in the genes encoding subunits of PI3K in TET samples. Sanger sequencing confirmation of mutations identified by MiSeq in (A) PIK3R2 in MP57 cells and PIK3CA in IU-TAB1 cells. (B) Sanger sequencing of mutations identified in PIK3CA, PIK3CG, and PIK3R4, in three TET primary tumor samples, respectively. Arrows indicate the mutated nucleotides.
