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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Int Forum Allergy Rhinol. 2015 Sep 8;5(12):1141–1150. doi: 10.1002/alr.21634

Figure 2. LL-37 causes inflammatory changes in the olfactory epithelium in a dose-dependent manner.

Figure 2

H&E showing the gradual histologic changes in (A) saline, (B) 80 μM LL-37, (C) 160 μM LL-37, and (D) 320 μM LL-37. Increased inflammatory cell infiltrates (Boxes in D; magnified image), thickness of the lamina propria (LP), and mucus (arrow) are demonstrated in 320 μM LL-37-treated mice. Dotted circles are represented by the magnified images in the bottom panel.