Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Catalytic reduction of lipid peroxides by GPX4. GPX4 (green) uses a highly nucleophilic selenocysteine to attack a lipid peroxide, generating a selenenic acid intermediate and a lipid hydroxide. The selenenic acid is further reduced by two successive equivalents of glutathione (GSH).
