. 2016 Sep;107(3 Suppl 3):18–24. doi: 10.5935/abc.20160154

Table 8.

Aggravating factors of CV risk

Aggravating factor	Recommendations and evidence
1. Family history of premature CAD in first-degree relative, men < 55 years or women < 65 years	GR: IIa; LE: A
2. Diagnosis of MS according to the IDF criteria	GR: IIb; LE: A
3. Microalbuminuria (30-300 mg/g creatinine) or albuminuria (> 300 mg/g creatinine)	GR: IIa; LE: B
4. LVH	GR: IIa; LE: B
5. High-sensitive C-reactive protein > 2 mg/L	GR: IIa; LE: B
6. Carotid IMT > 1.0 mm	GR: IIb; LE: B
7. Coronary calcium score > 100 or > 75^th percentile for age and sex	GR: IIa; LE: A
8. ABI < 0.9	GR: IIa; LE: A

CAD: coronary artery disease; MS: metabolic syndrome; IDF: International Diabetes Federation; LVH: left ventricular hypertrophy; IMT: intima-media thickness; ABI: ankle-brachial index.