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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Pac Symp Biocomput. 2016;22:27–38. doi: 10.1142/9789813207813_0004

Fig. 1.

Fig. 1

An example of the heterogeneous biological network under our function prediction framework. The node set V consists of four types, {“Human protein”, “Yeast protein”, “Mouse protein”, and “Gene Ontology term”}. The edge type set R consists of five types, {“Sequence similarity”, “Protein function annotation”,“Gene Ontology relationship”,“Experimental”, and “Co-expression”}. This HBN explicitly captures interolog and transfer of annotation through heterogeneous paths across different species.