Table 1.
Clinical characteristics according to ventricular arrhythmia type.
| Total (614) |
Idiopathic VT (N=177) |
Symptomatic PVC (N= 408) |
IVA-CM (N=29) |
P-value | |
|---|---|---|---|---|---|
| Age | 52.1 ± 17.2 | 59.2 ± 17.6 | 48.5 ± 15.8 | 59.2 ± 19.0 | <0.001 |
| EF, % | 62.1 (4.9) | 61.7 (4.8) | 62.7 (4.8) | 59.8 (9.1) | 0.004 |
| LVEDD, mm | 48.7 (5.2) | 49.5 (6.3) | 48.0 (4.3) | 50.5 (4.9) | 0.03 |
| DM | 62 (10%) | 21 (12%) | 37 (9%) | 4 (14%) | 0.468 |
| CKD | 28 (4%) | 10 (6%) | 11 (3%) | 2 (7%) | 0.148 |
| HTN | 243 (37%) | 84 (47%) | 121 (30%) | 15 (52%) | <0.001 |
| Hyperlipidemia | 312 (47%) | 90 (51%) | 178 (44%) | 17 (59%) | 0.110 |
| Hyperthyroid | 19 (3%) | 5 (3%) | 12 (3%) | 1 (3%) | 0.983 |
| Hypothyroid | 88 (13%) | 26 (15%) | 50 (12%) | 2 (7%) | 0.453 |
| Liver disease | 23 (4%) | 8 (5%) | 12 (3%) | 2 (7%) | 0.395 |
| Vaughan-Williams class* | |||||
| I | 22 (4%) | 8 (5%) | 6 (1%) | 8 (28%) | <0.001 |
| II | 254 (41%) | 83 (47%) | 147 (36%) | 24 (83%) | <0.001 |
| III | 20 (3%) | 11 (6%) | 2 (1%) | 7 (24%) | <0.001 |
| IV | 85 (14%) | 34 (19%) | 40 (10%) | 11 (38%) | <0.001 |
| PVC burden † | 5.3 ± 8.1 | 7.5 ± 9.9 | 3.8 ± 6 | 9.1 ± 11 | <0.001 |
| Stimulation as trigger ‡ | 14 (7%) | 13 (7%) | 1 (1%) | <0.001 | |
EF, ejection fraction; LVEDD, left ventricular end-diastolic diameter; PVC, premature ventricular complex; DM, Diabetes Mellitus; HTN, Hypertension; CKD, chronic kidney disease; IVA-CM, idiopathic ventricular arrhythmia-associated cardiomyopathy; VT, ventricular tachycardia.
*
Vaughn- Williams Classification is based on the action mechanism of drugs. Note that the numbers of patients treated with medications do not add up to 100%.
†
PVC Burden= PVC count/total number of beats expressed as %.
‡
Stimulation includes exercise, pain and caffeine.