Fig 1. Flow cytometry strategy to determine mitochondrial and membrane damage on monocytes from PBMC.
Panel A shows the FSC-H x SSC-H plot and the gate to select the monocyte population in cultured PBMCs. Panel B shows the DIOC6 x EB plot in monocytes from non-stimulated cultures. Panel C shows the DIOC6 x EB plot in monocytes PPD-stimulated cultures. Insets shows in panel A the percentage of cells within the monocyte gate, and in panels B and the percentage of cell with mitochondrial damage (DIOC6 low), membrane damage (EB+), or live cells DIOC6 high).