Fig 3. Pro- and anti-inflammatory cytokines´ expression was induced on cultured RAW cells after rTcHMGB treatment.

Relative cytokines´ mRNA levels at 3, 6 and 24 h of rTcHMGB, rGST or LPS treatment were determined by qRT-PCR using RPLP0 as housekeeping gene. Data are expressed as the fold change of the control non-treated group (white column) and presented as Mean ± SEM; * p<0.05. Cytokines analyzed were (A) TNF-α, (B) IL-1β, (C) TGF-β, (D) IL-10.