Skip to main content
. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Oct 13;100:109–117. doi: 10.1016/j.yjmcc.2016.10.005

Fig. 7.

Fig. 7

MMP-9 inhibition reduced apoptosis at D7 post-MI. (A) MMP-9i increased protein expression of full length caspase 3, an apoptosis marker, in the soluble fraction of the LVI. n = 6/group. (B) Cleaved caspase 3 expression was reduced in the MMP-9i LVI at D7 post-MI compared to saline LVI. Arrows depict positive staining. Scale bar is 200 μm. n = 12/group. (C) MMP-9i reduced TUNEL-positive staining at D7 post-MI. Arrows depict positive staining. Scale bar is 20 μm. n = 12/group. Overall, these data suggest compromised clearance of inflammatory cells. *p < 0.05 vs D0 and #p < 0.05 vs saline.