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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Anesth Analg. 2014 Sep;119(3):693–701. doi: 10.1213/ANE.0000000000000311

Figure 1.

Figure 1

The antiallodynic effect of interleukin (IL)-10 mediated by herpes simplex virus (HSV) vectors on neuropathic pain induced by human immunodeficiency virus (HIV) gp120. Mechanical allodynia in rats was shown day 7 after the gp120 administration (A). The gp120 injection (gp120) and the HSV vector (V) inoculation times are indicated by arrows. (A) QHIL10 resulted in a statistically significant elevation of the mechanical threshold (g) compared with the control vector (F(1,12) = 43.818, P < 0.001, repeated measures ANOVA, SPSS, n=7–8 rats, Figure 1A). For the comparison of differences at individual time points between groups, we used a two-tailed t test. Every P value is shown in the Figure. (B) The area under curves (AUC) in QHIL10 was significantly increased compared with Q0ZHG (P < 0.0001, t test, n=7–8 rats).