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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Anesth Analg. 2014 Sep;119(3):693–701. doi: 10.1213/ANE.0000000000000311

Figure 2.

Figure 2

The effect of interleukin (IL)-10 mediated by herpes simplex virus (HSV) vectors on the expression of phosphorylated p38 mitogen-activated kinase (p-p38) in the dorsal root ganglia (DRG) and spinal cord at 14 or 28 days. Rats with neuropathic pain were inoculated with QHIL10 or Q0ZHG on day 7 after gp120 administration. In the sham group, rats received Q0ZHG. (A and B) On day 14 after vector injection, the L4/5 DRG (A) and spinal dorsal horn (SDH) (B) were harvested, and expression of p-p38 was tested using Western blots. The data among three groups were compared using one way ANOVA with post hoc Fisher PLSD test, mean ± SEM, n=4 rats. The actual P values between sham+Q0ZHG and gp120+Q0ZHG group, or between gp120+Q0ZHG and gp120+QHIL10 are shown in Figure A and B. (C and D) On day 28 after vector injection, L4/5 DRG (C) and SDH (D) were harvested, and the expression of p-p38 was tested using Western blots. The actual P values between sham+Q0ZHG and gp120+Q0ZHG groups, or between gp120+Q0ZHG and gp120+QHIL10 groups are shown in Figure C and D, one way ANOVA with post hoc Fisher PLSD test, mean ± SEM, n=4 rats.