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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Bioorg Med Chem. 2016 Nov 10;25(3):813–824. doi: 10.1016/j.bmc.2016.11.013

Figure 2.

Figure 2

Sequence alignment of EcMetAP1 (PDB: 1XNZ)12 and RpMetAP1 (PDB: 3MX6) shaded according to alignment (dark = identity; light = similarity; no shading = non-conserved). Alignment reveals 53% identity between the proteins. Residues involved in cofactor binding are marked as X