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Isoprenoid biosynthesis in malaria parasites. The central stages (in pink) are performed by a single multi-functional farnesyl/geranylgeranyl diphosphate synthase (F/GGPPS). FPP and GGPP are precursors for the biosynthesis of many important isoprenoid products (in light green). DXP = deoxyxylulose-5-phosphate; DXR = deoxyxylulose-5-phosphate reductoisomerase; FTase = protein farnesyl transferase; OPPS = octaprenyl diphosphate synthase; PSY = phytoene synthase.
