TABLE 2.
Clinical Characteristics of CF Infants (N = 43)
| Variable | Mean (SD) or % |
|---|---|
| Genotype (F508del homozygous) | 56% |
| CFTR function (mean sweat chloride, mmol/L) | 98 (13.1) |
| iPFT | |
| FVC% | 108 (17.2) |
| FEV0.5% | 102 (19.9) |
| FEF25–75% | 96 (28.5) |
| RV/TLC% | 144 (24.6) |
| Nutritional status (weight/length percentile at 12 months) |
65% (24%) |
| Microbiology (history of PsA) | 44% |
| Cough (occasional/daily) | 42% |
| Pulmonary exacerbations (in first 12 months of life; range 1–5) |
1.9 (1.5) |
| Hospitalizations (in first 12 months of life) | 47% |
| Clinical score (range 0–10) | 7.6 (2.1) |
| Prescribed chronic pulmonary therapies | 67% |
| Inhaled corticosteroid | 42% |
| Dornase alpha | 40% |
| Azithromycin | 23% |