Table 2.
Variable selection results and model performance for the two follow-up times in the MSKCC cohort based on the candidate predictors in this cohort (cf. Table 1).
| MSKCC | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Follow-up: Short | Follow-up: Long | ||||||||||
| Model | AUC | Rs | p | β | pHL | Model | AUC | Rs | p | β | pHL |
| Dmeancontra* | 0.78 (0.07) | 0.46 (0.12) | 0.01 (0.07) | 0.14 | 0.51 (0.23) | Dmeancontra | 0.80 (0.07) | 0.28 (0.18) | 0.18 (0.21) | 0.07 | 0.39 (0.19) |
| Dmeanipsi* | 0.85 (0.06) | 0.50 (0.13) | 0.01 (0.04) | 0.09 | 0.24 (0.11) | Dmeanipsi | 0.73 (0.09) | 0.24 (0.16) | 0.25 (0.27) | 0.03 | 0.43 (0.10) |
| WMSFM Pre-RT* | 0.71 (0.09) | 0.45 (0.13) | 0.02 (0.08) | 0.84 | 0.51 (0.12) | ||||||
| Tumor site | 0.69 (0.08) | 0.28 (0.13) | 0.13 (0.20) | 0.14 | 0.46 (0.13) | ||||||
| Chemotherapy* | 0.65 (0.04) | 0.33 (0.07) | 0.04 (0.05) | 135 | 0.19 (0.07) | ||||||
| Dmeancontra+Dmeanipsi** | 0.90 (0.05) | 0.66 (0.12) | 0.0002 (0.002) | 0.17/0.11 | 0.22 (0.23) | ||||||
| WMSFM Pre-RT+Dmeanipsi | 0.85 (0.06) | 0.64 (0.12) | 0.001 (0.01) | 0.85/0.09 | 0.45 (0.24) | ||||||
Note: The AUC, Rs, p, and pHL are given as the mean ± standard deviation (SD) over the 1000 bootstrap samples.
*
Qualified for MVA,
**
Most frequently selected model (38%).