Table 5.

Severity of knee abnormalities in subjects stratified by age group. Severity presented as median (interquartile range) for subjects with any abnormality, i.e. WORMS score ≥ 1, for each feature. P-values are from Mann-Whitney U tests of scores from all subjects in each age group

	Baseline					Follow-up
	Adolescents (n = 18)		Adults (n = 18)			Adolescents (n = 18)		Adults (n = 18)
	n	Severity	n	Severity	p-value	n	Severity	n	Severity	p-value
Cartilage abnormalities	0	–	12	3 (2.5, 5)	–	0	–	13	3 (3, 5)	–
Bone marrow lesions	4	1 (1, 3)	8	2 (1, 2)	0.107	3	1 (1, 1.5)	11	2 (1, 2.5)	0.005
Subarticular cysts	2	1 (1, 1)	5	2 (1, 2)	0.169	2	1 (1, 1)	5	2 (1, 2)	0.169
Osteophytes	16	1 (1, 2)	18	3 (2, 5)	<0.001	16	2 (1, 2)	18	2.5 (2, 5)	<0.001
Ligamentous lesions	0	–	2	1 (1, 1)	0.151	0	–	2	1 (1, 1)	0.151
Meniscal lesions	5	1 (1, 1)	10	2 (2, 3)	0.021	5	1 (1, 1.3)	11	2 (2, 3.5)	0.015

P-values presented in bold capture demonstrate significance (p < 0.05)