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. 2017 Feb 22;11:29. doi: 10.3389/fnbeh.2017.00029

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Copyright © 2017 Holgate, Shariff, Mu and Bartlett.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Varenicline reduces sucrose consumption in DID rats following 30 min of sucrose access. (A) Administration of 2 mg/kg varenicline (gray) produced a significant reduction in sucrose consumption compared to saline (white) following 30 min of sucrose access using the DID model. Varenicline had no effect on sucrose consumption at the 2 h (B) and 4 h (C) time points n = 8 per group. Unpaired T-tests with Holm-Sidak correction (alpha = 0.017). ^##p < 0.01 compared to vehicle.