Table 2.

Loss of viability over time of mutants in SP-essential genes

		Fold reductiona in colony-forming units relative to Parentalb
		Days at 37°Cc				Days at 30°C
Gene	Strain	2	6	9	16	16
	parentalb	+d	+	+	+	+
ATP1	Δybl099w	10-2	-d	-	-	+e
ATP2	Δyjr121w	10-1	-	-	-	+e
QCR7	Δydr529c	+	10-3	-	-	10-1
SDH2	Δyll041c	+	10-3	-	-	10-3
RIP1	Δyel024w	+	10-2	-	-	+e
CIT1	Δynr001c	+	10-2	-	-	10-1
COX6	Δyhr051w	+	10-2	-	-	+e
SDH4	Δydr178w	+	10-2	-	-	+e
MDH1	Δykl085w	+	10-2	-	-	10-5
COX7	Δymr256c	+	+	10-4	-	10-2
ATP3	Δybr039w	+	10-1	10-2	-	10-1
KGD1	Δyil125w	+	10-1	10-2	-	10-1
ETR1	Δybr026c	+	+	10-2	-	+e
SOD2	Δyhr008c	+	+	10-2	-	+
ADY2	Δycr010c	+	+	10-2	-	+
MOH1	Δybl049w	+	+	10-1	-	+
HBT1	Δydl223c	+	+	10-1	-	+
GTT1	Δyir038c	+	+	10-2	10-3	+
SPG5	Δymr191w	+	+	+	10-3	+
CTA1	Δydr256c	+	+	+	10-3	+
POR1	Δynl055c	+	+	+	10-3	+
OM45	Δyil136w	+	+	+	10-2	+
FMP45	Δydl222c	+	+	+	10-2	+
FAA1	Δyor317w	+	+	10-1	10-2	+
SPG4	Δymr107w	+	+	10-1	10-1	+
PST2	Δydr032c	+	+	+	10-1	+
GLK1	Δycl040w	+	+	+	10-1	+
PNC1	Δygl037c	+	+	+	10-1	+

^aAverage from two or more experiments unless noted.

^bMATa BY4742 or MATa BY4741.

^cCultures were shifted to 37°C after 2 d of growth at 30°C.

^dNo reduction in viability (+), 10^-5 or more reduction in viability (-).

^eData from one experiment.