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. 2017 Feb 8;2017:9402615. doi: 10.1155/2017/9402615

Figure 10.

Figure 10

Antitumor effect of harmine in TPC-1 xenograft models. Tumor volume of established TPC-1 xenografts in nude mice during therapy under different treatments. Mice were treated with different protocols on Day 0 as shown in the figure. Saline: vehicle; harmine was administered at the doses of 10, 20, and 40 mg/kg. Different agents were delivered through intravenous pathway when tumor volume measured 100 mm3. Data are presented as mean ± SD (n = 6). The difference between tumor volumes in the group of saline and either 20 or 40 mg/kg of harmine is significant (∗∗ means p < 0.01 versus control). Significant difference (# means p < 0.05) also is observed between the groups receiving 40 mg/kg and 20 mg/kg harmine.