TABLE 2.
Events, n | Study participants, n | Model 12 | Model 23 | Model 34 | Model 45 | |
Meat, servings/d | NR | |||||
≤0.42 | 237 | 2877 | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) |
0.43–0.74 | 307 | 2757 | 1.39 (1.17, 1.65) | 1.33 (1.12, 1.58) | 1.38 (1.16, 1.65) | 1.30 (1.09, 1.55) |
0.75–1.10 | 318 | 2805 | 1.40 (1.18, 1.67) | 1.31 (1.10, 1.55) | 1.38 (1.16, 1.65) | 1.27 (1.06, 1.52) |
1.11–1.56 | 331 | 2798 | 1.46 (1.22, 1.74) | 1.33 (1.11, 1.59) | 1.45 (1.20, 1.74) | 1.26 (1.04, 1.52) |
≥1.57 | 376 | 2845 | 1.60 (1.32, 1.93) | 1.47 (1.22, 1.78) | 1.66 (1.36, 2.03) | 1.41 (1.15, 1.73) |
P-trend | <0.001 | <0.001 | <0.001 | 0.009 | ||
Fish and seafood, servings/d | NR | |||||
0–0.07 | 314 | 2752 | 1 (referent) | 1 (referent) | 1 (referent) | |
0.14 | 261 | 2429 | 0.96 (0.81, 1.13) | 0.97 (0.82, 1.15) | 0.97 (0.82, 1.15) | |
0.21–0.28 | 431 | 3972 | 0.95 (0.82, 1.11) | 0.98 (0.84, 1.14) | 0.97 (0.84, 1.13) | |
0.35–0.50 | 259 | 2291 | 0.99 (0.84, 1.18) | 1.04 (0.88, 1.23) | 1.04 (0.87, 1.23) | |
>0.50 | 304 | 2638 | 1.02 (0.87, 1.21) | 1.11 (0.94, 1.31) | 1.10 (0.92, 1.30) | |
P-trend | 0.693 | 0.172 | 0.238 | |||
Poultry, servings/d | NR | |||||
0–0.07 | 230 | 1933 | 1 (referent) | 1 (referent) | 1 (referent) | |
0.14 | 432 | 3764 | 0.98 (0.83, 1.15) | 0.97 (0.83, 1.15) | 0.96 (0.82, 1.13) | |
0.21–0.28 | 170 | 1581 | 0.95 (0.78, 1.16) | 1.01 (0.83, 1.24) | 1.00 (0.82, 1.23) | |
0.43 | 423 | 4017 | 0.88 (0.75, 1.04) | 0.96 (0.81, 1.13) | 0.95 (0.80, 1.12) | |
≥0.50 | 314 | 2787 | 1.00 (0.84, 1.20) | 1.12 (0.94, 1.34) | 1.12 (0.94, 1.35) | |
P-trend | 0.545 | 0.272 | 0.274 | |||
Dairy, servings/d | NR | |||||
≤0.56 | 322 | 2613 | 1 (referent) | 1 (referent) | 1 (referent) | |
0.57–1.13 | 320 | 2956 | 0.87 (0.75, 1.02) | 0.93 (0.79, 1.09) | 0.94 (0.80, 1.10) | |
1.14–1.56 | 307 | 2788 | 0.87 (0.74, 1.02) | 0.95 (0.81, 1.12) | 0.96 (0.81, 1.13) | |
1.57–2.49 | 299 | 2906 | 0.81 (0.69, 0.96) | 0.89 (0.75, 1.05) | 0.90 (0.76, 1.07) | |
≥2.50 | 321 | 2819 | 0.93 (0.78, 1.11) | 1.03 (0.86, 1.23) | 1.09 (0.90, 1.30) | |
P-trend | 0.291 | 0.978 | 0.648 | |||
Fruits, servings/d | NR | |||||
≤0.78 | 328 | 2852 | 1 (referent) | 1 (referent) | 1 (referent) | |
0.79–1.42 | 301 | 2750 | 0.95 (0.81, 1.11) | 1.04 (0.89, 1.22) | 1.03 (0.88, 1.21) | |
1.43–2.07 | 328 | 2852 | 0.98 (0.84, 1.15) | 1.13 (0.96, 1.32) | 1.13 (0.96, 1.33) | |
2.08–3.00 | 279 | 2792 | 0.81 (0.69, 0.96) | 1.01 (0.85, 1.19) | 1.02 (0.86, 1.21) | |
>3.00 | 333 | 2836 | 0.90 (0.77, 1.06) | 1.15 (0.97, 1.36) | 1.19 (1.00, 1.42) | |
P-trend | 0.062 | 0.202 | 0.102 | |||
Vegetables, servings/d | NR | |||||
≤1.08 | 313 | 2819 | 1 (referent) | 1 (referent) | 1 (referent) | |
1.12–1.55 | 320 | 2819 | 0.99 (0.85, 1.16) | 1.02 (0.87, 1.19) | 1.01 (0.86, 1.19) | |
1.56–2.13 | 295 | 2802 | 0.94 (0.80, 1.11) | 0.99 (0.84, 1.16) | 0.99 (0.84, 1.16) | |
2.13–2.91 | 307 | 2825 | 0.95 (0.80, 1.11) | 1.01 (0.85, 1.19) | 1.01 (0.86, 1.20) | |
>2.91 | 334 | 2817 | 0.98 (0.83, 1.17) | 1.06 (0.89, 1.26) | 1.07 (0.90, 1.28) | |
P-trend | 0.674 | 0.579 | 0.504 | |||
Whole grains, servings/d | NR | |||||
≤0.21 | 354 | 2800 | 1 (referent) | 1 (referent) | 1 (referent) | |
0.28–0.80 | 332 | 2981 | 0.94 (0.81, 1.09) | 0.99 (0.85, 1.16) | 0.99 (0.85, 1.15) | |
0.86–1.08 | 275 | 2504 | 0.90 (0.77, 1.06) | 1.02 (0.87, 1.20) | 1.02 (0.87, 1.20) | |
1.14–2.00 | 324 | 3106 | 0.89 (0.77, 1.04) | 1.08 (0.92, 1.27) | 1.08 (0.92, 1.27) | |
>2.00 | 284 | 2691 | 0.89 (0.76, 1.05) | 1.08 (0.92, 1.28) | 1.10 (0.93, 1.31) | |
P-trend | 0.114 | 0.210 | 0.158 | |||
Refined grains, servings/d | NR | |||||
≤1 | 301 | 2821 | 1 (referent) | 1 (referent) | 1 (referent) | |
1.01–1.62 | 292 | 2795 | 0.95 (0.81, 1.12) | 0.97 (0.82, 1.14) | 0.98 (0.84, 1.16) | |
1.63–2.35 | 312 | 2831 | 0.97 (0.82, 1.14) | 0.98 (0.83, 1.16) | 1.02 (0.86, 1.21) | |
2.36–3.51 | 321 | 2820 | 0.93 (0.78, 1.10) | 0.91 (0.77, 1.08) | 0.97 (0.81, 1.16) | |
≥3.52 | 343 | 2815 | 0.94 (0.78, 1.14) | 0.92 (0.76, 1.11) | 1.03 (0.84, 1.26) | |
P-trend | 0.503 | 0.279 | 0.894 | |||
Nuts, servings | NR | |||||
Almost never | 704 | 5780 | 1 (referent) | 1 (referent) | 1 (referent) | |
1–3/mo | 435 | 4253 | 0.90 (0.79, 1.01) | 0.93 (0.82, 1.05) | 0.94 (0.83, 1.06) | |
1/wk | 219 | 2154 | 0.87 (0.74, 1.01) | 0.92 (0.78, 1.07) | 0.93 (0.80, 1.09) | |
≥2/wk | 211 | 1893 | 0.95 (0.81, 1.12) | 1.01 (0.86, 1.19) | 1.04 (0.89, 1.23) | |
P-trend | 0.213 | 0.711 | 0.996 | |||
Coffee, servings | NR | |||||
0 | 439 | 3762 | 1 (referent) | 1 (referent) | 1 (referent) | |
1/mo to 6/wk | 198 | 1937 | 0.89 (0.75, 1.05) | 0.89 (0.75, 1.05) | 0.89 (0.75, 1.06) | |
1/d | 319 | 2734 | 0.93 (0.80, 1.07) | 0.89 (0.77, 1.03) | 0.89 (0.77, 1.03) | |
2–3/d | 346 | 3262 | 0.94 (0.81, 1.09) | 0.82 (0.71, 0.95) | 0.83 (0.72, 0.97) | |
≥4/d | 267 | 2387 | 1.13 (0.97, 1.33) | 0.84 (0.71, 0.99) | 0.84 (0.75, 1.00) | |
P-trend | 0.348 | 0.009 | 0.014 | |||
Tea, servings | NR | |||||
Almost never | 635 | 5378 | 1 (referent) | 1 (referent) | 1 (referent) | |
1/mo to 1/wk | 324 | 3076 | 0.90 (0.79, 1.03) | 0.94 (0.82, 1.08) | 0.94 (0.82, 1.08) | |
2–6/wk | 246 | 2271 | 0.92 (0.79, 1.07) | 0.99 (0.85, 1.16) | 0.99 (0.85, 1.16) | |
≥1/d | 364 | 3357 | 0.91 (0.79, 1.04) | 0.96 (0.84, 1.10) | 0.96 (0.84, 1.09) | |
P-trend | 0.101 | 0.550 | 0.529 | |||
Sugar-sweetened beverages, servings | NR | |||||
Almost never | 506 | 4440 | 1 (referent) | 1 (referent) | 1 (referent) | |
1–3/mo | 169 | 1611 | 0.84 (0.70, 1.00) | 0.86 (0.72, 1.03) | 0.87 (0.73, 1.04) | |
1/wk | 233 | 2069 | 0.85 (0.72, 0.99) | 0.89 (0.76, 1.04) | 0.89 (0.76, 1.05) | |
2–6/wk | 283 | 2822 | 0.71 (0.61, 0.82) | 0.71 (0.61, 0.83) | 0.74 (0.63, 0.86) | |
≥1/d | 377 | 3136 | 0.82 (0.70, 0.95) | 0.79 (0.68, 0.92) | 0.86 (0.73, 1.00) | |
P-trend | <0.001 | <0.001 | 0.005 | |||
Diet soda, servings | NR | |||||
Almost never | 714 | 6365 | 1 (referent) | 1 (referent) | 1 (referent) | |
1/mo to 1/wk | 249 | 2207 | 1.09 (0.94, 1.26) | 1.21 (1.04, 1.41) | 1.19 (1.02, 1.38) | |
2–6/wk | 220 | 2314 | 0.93 (0.80, 1.09) | 1.06 (0.91, 1.24) | 1.02 (0.87, 1.20) | |
≥1/d | 385 | 3195 | 1.25 (1.10, 1.42) | 1.35 (1.19, 1.54) | 1.31 (1.15, 1.49) | |
P-trend | 0.007 | <0.001 | <0.001 | |||
Alcohol, drinks/wk | NR | |||||
0 | 1012 | 8560 | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) |
1–6 | 290 | 3291 | 0.85 (0.74, 0.97) | 0.77 (0.67, 0.88) | 0.78 (0.68, 0.89) | 0.86 (0.75, 0.99) |
≥7 | 260 | 2203 | 1.09 (0.94, 1.26) | 0.84 (0.72, 0.98) | 0.89 (0.76, 1.04) | 1.00 (0.85, 1.18) |
P-trend | 0.813 | 0.011 | 0.024 |
NR, model not run.
Adjusted for age, sex, race/ethnicity, field center, education, height, and energy intake.
Adjusted as for model 1 plus for physical activity, baseline smoking status, and pack-years.
Adjusted as for model 2 plus for meat, dairy, fruits, vegetables, whole grains, and refined grains.
Adjusted as for model 3 plus for diabetes status, hypertension status, and HDL and LDL cholesterol.