TABLE 4.
Fecal water SCFA concentrations of participants at baseline (week 2) and follow-up (week 8)1
RG group |
WG group |
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Measure | Baseline | Follow-up | ΔRG | P | Baseline | Follow-up | ΔWG | P | ΔWG − ΔRG | P |
Acetate, mmol/L | 20.73 ± 1.11 | 19.3 ± 0.92 | −1.43 ± 0.96 | 0.03 | 21.63 ± 1.17 | 22.34 ± 1.26 | 0.71 ± 0.98 | 0.19 | 2.13 ± 1.36 | 0.02 |
Propionate, mmol/L | 5.19 ± 0.64 | 3.6 ± 0.5 | −1.59 ± 0.32 | <0.0001 | 5.37 ± 0.71 | 3.46 ± 0.46 | −1.91 ± 0.25 | <0.0001 | −0.32 ± 0.41 | 0.29 |
Butyrate, mmol/L | 5.29 ± 0.8 | 4.5 ± 0.51 | −0.79 ± 0.89 | 0.14 | 5.43 ± 0.7 | 5.52 ± 0.91 | 0.09 ± 0.76 | 0.86 | 0.88 ± 1.18 | 0.25 |
Total SCFAs, mmol/L | 31.21 ± 2.12 | 27.4 ± 1.62 | −3.81 ± 1.66 | 0.002 | 32.43 ± 2.1 | 31.32 ± 2.08 | −1.11 ± 1.51 | 0.65 | 2.70 ± 2.25 | 0.05 |
All values are means ± SEMs. n = 40 in the RG group, and n = 41 in the WG group. There were no differences between groups at baseline. P values were obtained with the use of an ANCOVA and controlling for the baseline measure, BMI, age, and sex. RG, refined grain; SCFA, short-chain fatty acid; WG, whole grain.