Table 1. Sperm molecules involved in sperm-oocyte fusion.

Molecule	Method	Fusion	Reference
ADAM2	Knockout	~ 50%	[35, 36]
α-L-Fucosidase	Antibodies against α-L-Fucosidase	Reduced	[78, 79]
BPI	Antibodies against BPI	Reduced	[51]
Calpains	Antibodies against Calpains	Reduced	[80]
CRISP1	Knockout	Reduced	[45]
CRISP2	Knockout	Reduced	[72]
ERp29	Antibodies against ERp29	Reduced	[75]
IZUMO1	Knockout	Failed	[15]
SLLP1	Antibodies against SLLP1	Reduced	[76]
SPACA6	Knockout	Failed	[81]
SPESP1	Knockout	Severely reduced	[39,40,41,42]
TSSK6	Knockout	Failed	[17]