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Autoimmune orchitis in rats. Animals were administered endogenous sperm emulsified with Freund′s complete adjuvant (FCA) twice with a 2-week interval in the immature period. Testes were examined histologically at 20 weeks of age. Control testis (after administration of FCA only, left) shows normal spermatogenesis, whereas sperm inoculation has caused autoimmune orchitis (right), resulting in complete aspermatogenesis. Scale bar = 100 μm.
