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. 2017 Feb 22;7:43016. doi: 10.1038/srep43016

Figure 1. The administration of soot particles for 5 hours induced the release of IL-1-like cytokines by murine macrophages.

Figure 1

J774.1 cells (a murine macrophage cell line) were treated with soot particles in a concentration-dependent manner (1 pg/ml–5 ng/ml) for 5 hours. LPS (0.1 μg/ml) and/or ATP (0.5 mM) was used as a positive control. The addition of soot particles to macrophages induced the release of IL-1β (A), IL-1α (B) and IL-33 (C). Data are presented as the means ± SEM (n = 12). Statistically significant differences are denoted by *, ** and ***, indicating p < 0.05, p < 0.01 and p < 0.001, respectively, as determined by one-way ANOVA followed by Bonferroni’s multiple comparison post-test.