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Overexpression of syndecan-4 bypasses the effects of tenascin-C. Wild-type REFs (A and B) or REFs overexpressing syndecan-4 (REF+s4) (C and D) were allowed to interact with fibrin-FN matrices with (B and D) or without (A and C) 70Ten for 1 h before staining for actin. Scale bar, 60 μm; inset, 10 μm. (E) Matrix contraction was measured for REF or REF+s4 cells in fibrin-FN or fibrin-FN + 70Ten matrix. Data are expressed as the average of two experiments.
