Table 2.
The univariate and multivariate logistic regression analysis
| Risk factor | Univariate logistic regression | Multivariate logistic regression | ||
|---|---|---|---|---|
| Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
| Age (in years) | 1.04 (1.01–1.08) | 0.0223 | 1.03 (0.99–1.03) | 0.1181 |
| Sex (female = 1, male = 2) | 0.51 (0.16–1.56) | 0.2365 | Not included | – |
| Thyroid function (1 – euthyroidism, 2 – hyperthyroidism, 3 – hypothyroidism) |
1.35 (0.76–2.40) | 0.3048 | Not included | – |
| Antithyroid drugs (1 – no, 2 – yes) |
0.95 (0.10–8.75) | 0.9605 | Not included | – |
| L-thyroxine supplementation (1 – no, 2 – yes) |
2.23 (1.00–4.98) | 0.0491 | 0.80 (0.29–2.27) | 0.6818 |
| Autoimmune thyroiditis (1 – no, 2 – yes) |
0.61 (0.12–3.19) | 0.5631 | Not included | – |
|
131I therapy (1 – no, 2 – yes) |
6.32 (2.71–14.72) | < 0.0001 | 4.84 (1.82–12.87) | 0.0016 |
| Surgery in the neck region (1 – no, 2 – yes) |
0.79 (0.21–2.94) | 0.7285 | Not included | – |
| Radiation therapy in the neck region (1 – no, 2 – yes) | 0.36 (0.04–2.91) | 0.3378 | Not included | – |
| Nodule size (mm) | 1.01 (0.97–1.05) | 0.6207 | Not included | – |
| Sonographic findings according to Kim’s classification (U2, U3, U4, U5) Time between the biopsies (days) |
0.80 (0.42–1.53) 1.0 (1.00–1.01) |
0.5022 0.2916 |
Not included Not included |
– – |