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. 2004 Dec;15(12):5700–5711. doi: 10.1091/mbc.E04-08-0732

Table 2.

Effects of topoII inhibition and depletion in HT1080 and HTETOP cells, respectively, on DNA bridge formation and mitotic index

HT1080
HTETOP
-ICRF-193 +ICRF 193a -doxycycline +doxycyclineb
DNA bridges (%) 0 4.7 2.7 17.9
MI (%) 1.9 0.4 2.4 1.9
a

8 μg/ml for 24 h

b

1 μg/ml for 48 h